INCREASING THE EXTRACTION COEFFICIENT OF THE RAW MATERIAL CENTELLA ASIATICA BY OPTIMIZING THE GRANULE SIZE OF THE RAW MATERIAL
Mahi LATIFI, Ejup LATIFI, Nazif JASHARI, Njomza LATIFI
Abstract
The preparation of the pharmaceutical plant raw material Centella asiatica is one of the key factors affecting the extraction coefficient and optimizing the extraction process. Regardless of the extraction method used, the granule size must be optimal for the process to be effective. This is primarily because an optimal granule size increases the active surface area of the raw material when it comes into contact with the solvent. While this is a general rule for the extraction process, it does not fully apply to Centella asiatica due to practical challenges. During extraction, granules can clump together, forming separate focul that hinder the process and reduce the extraction coefficient. Therefore, achieving an optimal granule size is crucial. On one hand, it ensures the extraction process is completed effectively; on the other hand, it maximizes the extraction coefficient by isolating the desired active substances from the raw material while preventing the extraction of undesirable accompanying substances, such as sugars, chlorophyll, and others, which can complicate the subsequent technological process.
Pages:
113 - 118