TREATMENT CORRELATION OF SIDEROPENIC ANEMIA WITH IRON (III) PROTEIN SUCCINYLATE (IPS) AND SUCROSOMIAL IRON (SI)

Sani Bajrami, Anita Sinani, Florin Besimi, Destan Haliti

Abstract

Introduction: Anaemia denotes a reduced number of erythrocytes or reduced amount of Hgb, or one and the other at the simultaneously, below the reference values for the appropriate age. Iron is a metal taken-in by ingestion and it is crucial for haemoglobin synthesis, and saturation of its storage. During the different ages of life, and in infants also, the daily iron needs increases, and if this need is not compensated, hypochromic anaemia develops. Purpose: This paper aims to determine the time ratio and the results of the treatment of iron-deficiency anaemia with IronProteinSuccinylate and Sucrosomial Iron. Materials and Methods: The prospective study was performed during the screening of anaemia in infants at the PHI – PEDIATRIKA in Tetovo and the clinical laboratory at the Clinical Hospital of Tetovo; 76 infants aged 1-12 months were screened, diagnosed with anaemia and treated during the period of January – June 2018. At the average age of 7.4 months, the gender composition was as follows: 47 infants are females, and 29 are males. Results: The results obtained at the beginning and after treatment with anti-anaemia therapy in both groups were analysed. The group that had been treated with Sucrosomial Iron has shown significant improvement of some parameters such as Hgb, HTC, MCV and Fe++ after using therapy for 1 month, while the group of patients treated with Iron Protein Succinylate has had a significantly weaker improvement compared to the first group. Conclusion: Sucrosomial Irontreatment has been shown to be most effective in the largest percentage of patients with Iron-deficiency anaemia, with parameters such as Hgb, HCT, MCV and Fe++ having higher growth in the group treated with Sucrosomial Iron for a period of 1 month. Discussion: The infant’s feeding habits are very important and affect the results of the treatment of anaemia; iron-rich food products and the use of supplementary therapy that is known of not having side effects, and that shortens the treatment period are recommended.

Pages: 133 - 139