RABDOMYOLISIS AND ACUTE RENAL FAILURE IN A PATIENT WITH COVID-19

T. STOJANOSKA, I. DEMIRI, S. BOGOEVA, M. KARTALOVA, M. HASIPI, M. CVETANOVSKA

Abstract

COVID-19 is characterized by a hyperactive immune reaction, causing a generalized systemic inflammatory response that most often manifests clinically as a febrile syndrome with respiratory symptoms, but there is a wide range of clinical concomitants that can equally appear as a consequence of Sars viral infection. CoV-2. Not sparing any organ system, Sars nCoV-2, in addition to the most common respiratory component of clinical presentation, equally affects other peripheral systems such as the cardiovascular system, the central nervous system, kidneys, muscles, etc. Even in the presence of the previous strains, cases of rhabdomyolysis and kidney infection were detected, but from the clinical experiences so far, with the appearance of the omicron variant in clinical practice, the frequency of patients whose clinical picture was dominated by myositis significantly increased, and in a certain group of older patients and rhabdomyolysis affecting kidney function. Rhabdomyolysis is a life-threatening disorder that presents with myalgia, fatigue, and pigmenturia, and may also present as acute renal failure. Precipitating factors for rhabdomyolysis include autoimmune myopathies, septicemia, electrolyte abnormalities, substance abuse, alcohol use, or infection. A viral infection, especially an infection with the influenza virus, can lead to rhabdomyolysis. Through this case report, the occurrence of rhabdomyolysis with acute real weakness in a patient with a severe form of COVID19 will be evaluated.

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