EXTRAINTESTINAL MANIFESTATIONS OF CROHN’s DISEASE

Ferizat Dika – Haxhirexha, Agron Dogjani, Lutfi Zylbeari, Ledia Kaçi, Vjosa Elezi, Kastriot Haxhirexha

Abstract

Extraintestinal manifestations of Crohn’s disease are common and are the consequence of the autoimmune inflammatory pathology into organs outside of the gastrointestinal system such as hepatobiliary tree, pancreas, skin, eyes and oral cavity. Case report: a 58 -years-old male patient was referred to our Department due to severe abdominal pain. The patient medical history show that he has suffered from Crohn’s disease for fifteen years. He has resection of terminal ileum in 2009. After that he has treated because of constriction at the major duodenal papilla and bile duct prosthesis was inserted. For five years the remission of disease was maintained with azathioprine. Three months after stopping the therapy with azathioprine, he began to complain for upper abdominal pain and in the back. After admission in our Department abdominal CT with contrast show the change in pancreas, whereas the leukocyte count was 30 ×109/L, CRP level - 98 mg/L, and severe hypoalbuminemia - 22 g/liter was present. Patient was sent to the reanimatory unit for intensive care and treatment. Conclusion: Crohn disease is a systemic disease which may be associated with many extraintestinal manifestations. For these reason it is very important to understand the complexity of this disease which require systemic treatment of autoimmune disturbances.

Pages: 54 - 56